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CRISPR type II-A subgroups exhibit phylogenetically distinct mechanisms for prespacer insertion

CRISPR-Cas is an adaptive immune system that protects prokaryotes against foreign nucleic acids. Prokaryotes gain immunity by acquiring short pieces of the invading nucleic acid termed prespacers and inserting them into their CRISPR array. In type II-A systems, Cas1 and Cas2 proteins insert prespace...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Van Orden, Mason J., Newsom, Sydney, Rajan, Rakhi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7415960/
https://ncbi.nlm.nih.gov/pubmed/32513871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013554
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