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Cas4-dependent prespacer processing ensures high-fidelity programming of CRISPR arrays
CRISPR-Cas immune systems integrate short segments of foreign DNA as spacers into the host CRISPR locus to provide molecular memory of infection. Cas4 proteins are widespread in CRISPR-Cas systems and are thought to participate in spacer acquisition, although their exact function remains unknown. He...
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| Publié dans: | Mol Cell |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5889325/ https://ncbi.nlm.nih.gov/pubmed/29602742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.03.003 |
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