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Exploiting CRISPR/Cas systems for biotechnology

The Cas9 endonuclease is the central component of the Type II CRISPR/Cas system, a prokaryotic adaptive restriction system against invading nucleic acids, such as those originating from bacteriophages and plasmids. Recently, this RNA-directed DNA endonuclease has been harnessed to target DNA sequenc...

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Detalhes bibliográficos
Publicado no:Bioessays
Main Authors: Sampson, Timothy R., Weiss, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385387/
https://ncbi.nlm.nih.gov/pubmed/24323919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300135
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