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Degeneration of a CRISPR/Cas system and its regulatory target during the evolution of a pathogen

CRISPR/Cas systems are bacterial RNA-guided endonuclease machineries that target foreign nucleic acids. Recently, we demonstrated that the Cas protein Cas9 controls gene expression and virulence in Francisella novicida by altering the stability of the mRNA for an immunostimulatory bacterial lipoprot...

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Bibliografski detalji
Glavni autori: Sampson, Timothy R, Weiss, David S
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866243/
https://ncbi.nlm.nih.gov/pubmed/24100224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.26423
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