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Degeneration of a CRISPR/Cas system and its regulatory target during the evolution of a pathogen
CRISPR/Cas systems are bacterial RNA-guided endonuclease machineries that target foreign nucleic acids. Recently, we demonstrated that the Cas protein Cas9 controls gene expression and virulence in Francisella novicida by altering the stability of the mRNA for an immunostimulatory bacterial lipoprot...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3866243/ https://ncbi.nlm.nih.gov/pubmed/24100224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.26423 |
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