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Exploiting CRISPR/Cas systems for biotechnology
The Cas9 endonuclease is the central component of the Type II CRISPR/Cas system, a prokaryotic adaptive restriction system against invading nucleic acids, such as those originating from bacteriophages and plasmids. Recently, this RNA-directed DNA endonuclease has been harnessed to target DNA sequenc...
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| Veröffentlicht in: | Bioessays |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4385387/ https://ncbi.nlm.nih.gov/pubmed/24323919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300135 |
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