Cilastatin protects against imipenem-induced nephrotoxicity via inhibition of renal organic anion transporters (OATs)

Imipenem is a carbapenem antibiotic. However, Imipenem could not be marketed owing to its instability and nephrotoxicity until cilastatin, an inhibitor of renal dehydropeptidase-I (DHP-I), was developed. In present study, the potential roles of renal organic anion transporters (OATs) in alleviating...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Acta Pharm Sin B
Main Authors: Huo, Xiaokui, Meng, Qiang, Wang, Changyuan, Zhu, Yanna, Liu, Zhihao, Ma, Xiaodong, Ma, Xiaochi, Peng, Jinyong, Sun, Huijun, Liu, Kexin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2019
Ábhair:
Original article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6804466/
https://ncbi.nlm.nih.gov/pubmed/31649848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2019.02.005
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla