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Piperacillin enhances the inhibitory effect of tazobactam on β-lactamase through inhibition of organic anion transporter 1/3 in rats
To assess the mechanism of the pharmacokinetic interaction between piperacillin and tazobactam, renal excretion and pharmacokinetic studies of piperacillin/tazobactam were investigated in normal and bacteremia rats. A bacteremia model was established to investigate the pharmacokinetic properties of...
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| 發表在: | Asian J Pharm Sci |
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| Main Authors: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Shenyang Pharmaceutical University
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7032209/ https://ncbi.nlm.nih.gov/pubmed/32104494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2018.11.003 |
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