Enhanced Mitochondrial Inhibition by 3,4-Dihydroxyphenyl-Acetaldehyde (DOPAL)-Oligomerized α-Synuclein

Oligomeric forms of α-synuclein are believed to cause mitochondrial injury, which may contribute to neurotoxicity in Parkinson’s disease (PD). Here oligomers of α-synuclein were prepared using the dopamine metabolite, DOPAL (3,4-dihydroxyphenyl-acetaldehyde), in the presence of guanidinium hydrochlo...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Neurosci Res
Hlavní autoři: Sarafian, Theodore A., Yacoub, Amneh, Kunz, Anastasia, Aranki, Burkan, Serobyan, Grigor, Cohn, Whitaker, Whitelegge, Julian P, Watson, Joseph B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6801072/
https://ncbi.nlm.nih.gov/pubmed/31420910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.24513
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky