Divalent Metal Ions Enhance DOPAL-induced Oligomerization of Alpha-Synuclein

Parkinson disease (PD) features profound striatal dopamine depletion and Lewy bodies containing abundant precipitated alpha-synuclein. Mechanisms linking alpha-synucleinopathy with the death of dopamine neurons remain incompletely understood. One such link may be 3,4-dihydroxyphenylacetaldehyde (DOP...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Jinsmaa, Yunden, Sullivan, Patricia, Gross, Daniel, Cooney, Adele, Sharabi, Yehonatan, Goldstein, David S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061610/
https://ncbi.nlm.nih.gov/pubmed/24670480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2014.03.016
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