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DOPAL is Transmissible to and Oligomerizes Alpha-Synuclein in Human Glial Cells
INTRODUCTION: Glial cytoplasmic inclusions (GCIs) containing alpha-synuclein (AS) are a neuropathologic hallmark of multiple system atrophy (MSA). Oligomerized AS is thought to be the pathogenic form of the protein. Glial cells normally express little AS, but they can take up AS from the extracellul...
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| Pubblicato in: | Auton Neurosci |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724267/ https://ncbi.nlm.nih.gov/pubmed/26777075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.autneu.2015.12.008 |
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