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DOPAL is Transmissible to and Oligomerizes Alpha-Synuclein in Human Glial Cells

INTRODUCTION: Glial cytoplasmic inclusions (GCIs) containing alpha-synuclein (AS) are a neuropathologic hallmark of multiple system atrophy (MSA). Oligomerized AS is thought to be the pathogenic form of the protein. Glial cells normally express little AS, but they can take up AS from the extracellul...

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書目詳細資料
發表在:Auton Neurosci
Main Authors: Jinsmaa, Yunden, Sullivan, Patricia, Sharabi, Yehonatan, Goldstein, David S.
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724267/
https://ncbi.nlm.nih.gov/pubmed/26777075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.autneu.2015.12.008
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