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DOPAL is Transmissible to and Oligomerizes Alpha-Synuclein in Human Glial Cells

INTRODUCTION: Glial cytoplasmic inclusions (GCIs) containing alpha-synuclein (AS) are a neuropathologic hallmark of multiple system atrophy (MSA). Oligomerized AS is thought to be the pathogenic form of the protein. Glial cells normally express little AS, but they can take up AS from the extracellul...

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Publicat a:Auton Neurosci
Autors principals: Jinsmaa, Yunden, Sullivan, Patricia, Sharabi, Yehonatan, Goldstein, David S.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724267/
https://ncbi.nlm.nih.gov/pubmed/26777075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.autneu.2015.12.008
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