A carregar...

3,4-Dihydroxyphenylacetaldehyde-Induced Protein Modifications and Their Mitigation by N-Acetylcysteine

The catecholaldehyde hypothesis posits that 3,4-dihydroxyphenylacetaldehyde (DOPAL), an obligate intermediary metabolite of dopamine, is an autotoxin that challenges neuronal homeostasis in catecholaminergic neurons. DOPAL toxicity may involve protein modifications, such as oligomerization of α-synu...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Jinsmaa, Yunden, Sharabi, Yehonatan, Sullivan, Patti, Isonaka, Risa, Goldstein, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5988001/
https://ncbi.nlm.nih.gov/pubmed/29700232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.118.248492
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!