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Elevated cerebrospinal fluid ratios of cysteinyl-dopamine/3,4-dihydroxyphenylacetic acid in parkinsonian synucleinopathies

INTRODUCTION: There is intense interest in identifying cerebrospinal fluid (CSF) biomarkers of Parkinson's disease (PD), both for early diagnosis and to track effects of putative treatments. Nigrostriatal dopamine depletion characterizes PD. Predictably, CSF levels of 3,4-dihydroxyphenylacetic...

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Detalhes bibliográficos
Publicado no:Parkinsonism Relat Disord
Main Authors: Goldstein, David S., Holmes, Courtney, Sullivan, Patricia, Jinsmaa, Yunden, Kopin, Irwin J., Sharabi, Yehonatan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125945/
https://ncbi.nlm.nih.gov/pubmed/27474472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2016.07.009
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