Elevated cerebrospinal fluid ratios of cysteinyl-dopamine/3,4-dihydroxyphenylacetic acid in parkinsonian synucleinopathies

INTRODUCTION: There is intense interest in identifying cerebrospinal fluid (CSF) biomarkers of Parkinson's disease (PD), both for early diagnosis and to track effects of putative treatments. Nigrostriatal dopamine depletion characterizes PD. Predictably, CSF levels of 3,4-dihydroxyphenylacetic...

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Vydáno v:Parkinsonism Relat Disord
Hlavní autoři: Goldstein, David S., Holmes, Courtney, Sullivan, Patricia, Jinsmaa, Yunden, Kopin, Irwin J., Sharabi, Yehonatan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125945/
https://ncbi.nlm.nih.gov/pubmed/27474472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2016.07.009
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