Elevated cerebrospinal fluid ratios of cysteinyl-dopamine/3,4-dihydroxyphenylacetic acid in parkinsonian synucleinopathies

INTRODUCTION: There is intense interest in identifying cerebrospinal fluid (CSF) biomarkers of Parkinson's disease (PD), both for early diagnosis and to track effects of putative treatments. Nigrostriatal dopamine depletion characterizes PD. Predictably, CSF levels of 3,4-dihydroxyphenylacetic...

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Bibliographic Details
Published in:Parkinsonism Relat Disord
Main Authors: Goldstein, David S., Holmes, Courtney, Sullivan, Patricia, Jinsmaa, Yunden, Kopin, Irwin J., Sharabi, Yehonatan
Format: Artigo
Language:Inglês
Published: 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125945/
https://ncbi.nlm.nih.gov/pubmed/27474472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2016.07.009
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