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Elevated cerebrospinal fluid ratios of cysteinyl-dopamine/3,4-dihydroxyphenylacetic acid in parkinsonian synucleinopathies

INTRODUCTION: There is intense interest in identifying cerebrospinal fluid (CSF) biomarkers of Parkinson's disease (PD), both for early diagnosis and to track effects of putative treatments. Nigrostriatal dopamine depletion characterizes PD. Predictably, CSF levels of 3,4-dihydroxyphenylacetic...

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Bibliografiske detaljer
Udgivet i:Parkinsonism Relat Disord
Main Authors: Goldstein, David S., Holmes, Courtney, Sullivan, Patricia, Jinsmaa, Yunden, Kopin, Irwin J., Sharabi, Yehonatan
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125945/
https://ncbi.nlm.nih.gov/pubmed/27474472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.parkreldis.2016.07.009
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