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3,4-Dihydroxyphenylethanol (Hydroxytyrosol) Mitigates the Increase in Spontaneous Oxidation of Dopamine during Monoamine Oxidase Inhibition in PC12 Cells

The catecholaldehyde hypothesis predicts that monoamine oxidase (MAO) inhibition should slow the progression of Parkinson’s disease, by decreasing production of the autotoxic dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL). Inhibiting MAO, however, diverts the fate of cytoplasmic dopamin...

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Detalhes bibliográficos
Publicado no:Neurochem Res
Main Authors: Goldstein, David S., Jinsmaa, Yunden, Sullivan, Patti, Holmes, Courtney, Kopin, Irwin J., Sharabi, Yehonatan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125943/
https://ncbi.nlm.nih.gov/pubmed/27220335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-016-1959-0
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