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3,4-Dihydroxyphenylethanol (Hydroxytyrosol) Mitigates the Increase in Spontaneous Oxidation of Dopamine during Monoamine Oxidase Inhibition in PC12 Cells

The catecholaldehyde hypothesis predicts that monoamine oxidase (MAO) inhibition should slow the progression of Parkinson’s disease, by decreasing production of the autotoxic dopamine metabolite 3,4-dihydroxyphenylacetaldehyde (DOPAL). Inhibiting MAO, however, diverts the fate of cytoplasmic dopamin...

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書誌詳細
出版年:Neurochem Res
主要な著者: Goldstein, David S., Jinsmaa, Yunden, Sullivan, Patti, Holmes, Courtney, Kopin, Irwin J., Sharabi, Yehonatan
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125943/
https://ncbi.nlm.nih.gov/pubmed/27220335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11064-016-1959-0
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