Distinct Functions for Anterograde and Retrograde Sorting of SORLA in Amyloidogenic Processes in the Brain

SORLA is a neuronal sorting receptor implicated both in sporadic and familial forms of AD. SORLA reduces the amyloidogenic burden by two mechanisms, either by rerouting internalized APP molecules from endosomes to the trans-Golgi network (TGN) to prevent proteolytic processing or by directing newly...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Dumanis, Sonya B., Burgert, Tilman, Caglayan, Safak, Füchtbauer, Annette, Füchtbauer, Ernst-Martin, Schmidt, Vanessa, Willnow, Thomas E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2015
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795211/
https://ncbi.nlm.nih.gov/pubmed/26377460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0427-15.2015
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia