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Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing

sorLA is a sorting receptor for amyloid precursor protein (APP) genetically linked to Alzheimer's disease (AD). Retromer, an adaptor complex in the endosome-to-Golgi retrieval pathway, has been implicated in APP transport because retromer deficiency leads to aberrant APP sorting and processing...

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Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Fjorback, Anja W., Seaman, Matthew, Gustafsen, Camilla, Mehmedbasic, Arnela, Gokool, Suzanne, Wu, Chengbiao, Militz, Daniel, Schmidt, Vanessa, Madsen, Peder, Nyengaard, Jens R., Willnow, Thomas E., Christensen, Erik Ilsø, Mobley, William B., Nykjær, Anders, Andersen, Olav M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796259/
https://ncbi.nlm.nih.gov/pubmed/22279231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2272-11.2012
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