Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing

sorLA is a sorting receptor for amyloid precursor protein (APP) genetically linked to Alzheimer's disease (AD). Retromer, an adaptor complex in the endosome-to-Golgi retrieval pathway, has been implicated in APP transport because retromer deficiency leads to aberrant APP sorting and processing...

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Publicado en:J Neurosci
Main Authors: Fjorback, Anja W., Seaman, Matthew, Gustafsen, Camilla, Mehmedbasic, Arnela, Gokool, Suzanne, Wu, Chengbiao, Militz, Daniel, Schmidt, Vanessa, Madsen, Peder, Nyengaard, Jens R., Willnow, Thomas E., Christensen, Erik Ilsø, Mobley, William B., Nykjær, Anders, Andersen, Olav M.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2012
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796259/
https://ncbi.nlm.nih.gov/pubmed/22279231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2272-11.2012
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