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Retromer Binds the FANSHY Sorting Motif in SorLA to Regulate Amyloid Precursor Protein Sorting and Processing

sorLA is a sorting receptor for amyloid precursor protein (APP) genetically linked to Alzheimer's disease (AD). Retromer, an adaptor complex in the endosome-to-Golgi retrieval pathway, has been implicated in APP transport because retromer deficiency leads to aberrant APP sorting and processing...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Fjorback, Anja W., Seaman, Matthew, Gustafsen, Camilla, Mehmedbasic, Arnela, Gokool, Suzanne, Wu, Chengbiao, Militz, Daniel, Schmidt, Vanessa, Madsen, Peder, Nyengaard, Jens R., Willnow, Thomas E., Christensen, Erik Ilsø, Mobley, William B., Nykjær, Anders, Andersen, Olav M.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796259/
https://ncbi.nlm.nih.gov/pubmed/22279231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2272-11.2012
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