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SORLA-Dependent and -Independent Functions for PACS1 in Control of Amyloidogenic Processes

Sorting-related receptor with A-type repeats (SORLA) is a sorting receptor for the amyloid precursor protein (APP) that prevents breakdown of APP into Aβ peptides, a hallmark of Alzheimer's disease (AD). Several cytosolic adaptors have been shown to interact with the cytoplasmic domain of SORLA...

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Detalhes bibliográficos
Main Authors: Burgert, Tilman, Schmidt, Vanessa, Caglayan, Safak, Lin, Fuyu, Füchtbauer, Annette, Füchtbauer, Ernst-Martin, Nykjaer, Anders, Carlo, Anne-Sophie, Willnow, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811889/
https://ncbi.nlm.nih.gov/pubmed/24001769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00628-13
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