Distinct Functions for Anterograde and Retrograde Sorting of SORLA in Amyloidogenic Processes in the Brain

SORLA is a neuronal sorting receptor implicated both in sporadic and familial forms of AD. SORLA reduces the amyloidogenic burden by two mechanisms, either by rerouting internalized APP molecules from endosomes to the trans-Golgi network (TGN) to prevent proteolytic processing or by directing newly...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Neurosci
Main Authors: Dumanis, Sonya B., Burgert, Tilman, Caglayan, Safak, Füchtbauer, Annette, Füchtbauer, Ernst-Martin, Schmidt, Vanessa, Willnow, Thomas E.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2015
主題:
Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795211/
https://ncbi.nlm.nih.gov/pubmed/26377460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0427-15.2015
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍