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Prion strain-dependent tropism is maintained between spleen and granuloma and relies on lymphofollicular structures

In peripherally acquired prion diseases, prions move through several tissues of the infected host, notably in the lymphoid tissue, long before the occurrence of neuroinvasion. Accumulation can even be restricted to the lymphoid tissue without neuroinvasion and clinical disease. Several experimental...

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Publicat a:Sci Rep
Autors principals: Al-Dybiat, Iman, Moudjou, Mohammed, Martin, Davy, Reine, Fabienne, Herzog, Laetitia, Truchet, Sandrine, Berthon, Patricia, Laude, Hubert, Rezaei, Human, Andréoletti, Olivier, Béringue, Vincent, Sibille, Pierre
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787085/
https://ncbi.nlm.nih.gov/pubmed/31601984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51084-1
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