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Host prion protein expression levels impact prion tropism for the spleen
Prions are pathogens formed from abnormal conformers (PrP(Sc)) of the host-encoded cellular prion protein (PrP(C)). PrP(Sc) conformation to disease phenotype relationships extensively vary among prion strains. In particular, prions exhibit a strain-dependent tropism for lymphoid tissues. Prions can...
Tallennettuna:
| Julkaisussa: | PLoS Pathog |
|---|---|
| Päätekijät: | , , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7402522/ https://ncbi.nlm.nih.gov/pubmed/32702070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008283 |
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