Prion strain-dependent tropism is maintained between spleen and granuloma and relies on lymphofollicular structures

In peripherally acquired prion diseases, prions move through several tissues of the infected host, notably in the lymphoid tissue, long before the occurrence of neuroinvasion. Accumulation can even be restricted to the lymphoid tissue without neuroinvasion and clinical disease. Several experimental...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Al-Dybiat, Iman, Moudjou, Mohammed, Martin, Davy, Reine, Fabienne, Herzog, Laetitia, Truchet, Sandrine, Berthon, Patricia, Laude, Hubert, Rezaei, Human, Andréoletti, Olivier, Béringue, Vincent, Sibille, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6787085/
https://ncbi.nlm.nih.gov/pubmed/31601984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51084-1
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