Highly Infectious Prions Generated by a Single Round of Microplate-Based Protein Misfolding Cyclic Amplification

Measurements of the presence of prions in biological tissues or fluids rely more and more on cell-free assays. Although protein misfolding cyclic amplification (PMCA) has emerged as a valuable, sensitive tool, it is currently hampered by its lack of robustness and rapidity for high-throughput purpos...

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Main Authors: Moudjou, Mohammed, Sibille, Pierre, Fichet, Guillaume, Reine, Fabienne, Chapuis, Jérôme, Herzog, Laetitia, Jaumain, Emilie, Laferrière, Florent, Richard, Charles-Adrien, Laude, Hubert, Andréoletti, Olivier, Rezaei, Human, Béringue, Vincent
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884057/
https://ncbi.nlm.nih.gov/pubmed/24381300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00829-13
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