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Accelerated, Spleen-Based Titration of Variant Creutzfeldt-Jakob Disease Infectivity in Transgenic Mice Expressing Human Prion Protein with Sensitivity Comparable to That of Survival Time Bioassay

The dietary exposure of the human population to the prions responsible for the bovine spongiform encephalopathy (BSE) epizooty has led to the emergence of variant Creutzfeldt-Jakob disease (vCJD). This fatal, untreatable neurodegenerative disorder is a growing public health concern because the preva...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Halliez, Sophie, Reine, Fabienne, Herzog, Laetitia, Jaumain, Emilie, Haïk, Stéphane, Rezaei, Human, Vilotte, Jean-Luc, Laude, Hubert, Béringue, Vincent
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135959/
https://ncbi.nlm.nih.gov/pubmed/24850746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01118-14
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