Loading...

Dose‐linearity of the pharmacokinetics of an intravenous [(14)C]midazolam microdose in children

AIMS: Drug disposition in children may vary from adults due to age‐related variation in drug metabolism. Microdose studies present an innovation to study pharmacokinetics (PK) in paediatrics; however, they should be used only when the PK is dose linear. We aimed to assess dose linearity of a [(14)C]...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Br J Clin Pharmacol
Main Authors: van Groen, Bianca D., Vaes, Wouter H., Park, B. Kevin, Krekels, Elke H.J., van Duijn, Esther, Kõrgvee, Lenne‐Triin, Maruszak, Wioleta, Grynkiewicz, Grzegorz, Garner, R. Colin, Knibbe, Catherijne A.J., Tibboel, Dick, de Wildt, Saskia N., Turner, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783587/
https://ncbi.nlm.nih.gov/pubmed/31269280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14047
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!