Yüklüyor......

The Oral Bioavailability and Metabolism of Midazolam in Stable Critically Ill Children: A Pharmacokinetic Microtracing Study

Midazolam is metabolized by the developmentally regulated intestinal and hepatic drug‐metabolizing enzyme cytochrome P450 (CYP) 3A4/5. It is frequently administered orally to children, yet knowledge is lacking on the oral bioavailability in term neonates up until 1 year of age. Furthermore, the disp...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Clin Pharmacol Ther
Asıl Yazarlar: van Groen, Bianca D., Krekels, Elke H. J., Mooij, Miriam G., van Duijn, Esther, Vaes, Wouter H. J., Windhorst, Albert D., van Rosmalen, Joost, Hartman, Stan J. F., Hendrikse, N. Harry, Koch, Birgit C. P., Allegaert, Karel, Tibboel, Dick, Knibbe, Catherijne A. J., de Wildt, Saskia N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818442/
https://ncbi.nlm.nih.gov/pubmed/32403162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1890
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!