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Expression of Human Apolipoprotein E3 or E4 in the Brains ofApoe(−/−) Mice: Isoform-Specific Effects on Neurodegeneration
Apolipoprotein (apo) E isoforms are key determinants of susceptibility to Alzheimer’s disease. The apoE4 isoform is the major known genetic risk factor for this disease and is also associated with poor outcome after acute head trauma or stroke. To test the hypothesis that apoE3, but not apoE4, prote...
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| Udgivet i: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for Neuroscience
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6782676/ https://ncbi.nlm.nih.gov/pubmed/10366621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.19-12-04867.1999 |
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