HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus

BACKGROUND: HIV-1 proviruses can persist during ART in clonally-expanded populations of CD4+ T cells. To date, few examples of an expanded clones containing replication-competent proviruses exist, although it is suspected to be common. One such clone, denoted AMBI-1 (Maldarelli et al., 2014), was al...

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Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Musick, Andrew, Spindler, Jonathan, Boritz, Eli, Pérez, Liliana, Crespo-Vélez, Daniel, Patro, Sean C., Sobolewski, Michele D., Bale, Michael J., Reid, Carolyn, Keele, Brandon F., Capoferri, Adam, Shao, Wei, Wiegand, Ann, Simonetti, Francesco R., Mellors, John W., Hughes, Stephen H., Coffin, John M., Maldarelli, Frank, Kearney, Mary F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781911/
https://ncbi.nlm.nih.gov/pubmed/31632364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02204
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