HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus

BACKGROUND: HIV-1 proviruses can persist during ART in clonally-expanded populations of CD4+ T cells. To date, few examples of an expanded clones containing replication-competent proviruses exist, although it is suspected to be common. One such clone, denoted AMBI-1 (Maldarelli et al., 2014), was al...

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Dades bibliogràfiques
Publicat a:Front Microbiol
Autors principals: Musick, Andrew, Spindler, Jonathan, Boritz, Eli, Pérez, Liliana, Crespo-Vélez, Daniel, Patro, Sean C., Sobolewski, Michele D., Bale, Michael J., Reid, Carolyn, Keele, Brandon F., Capoferri, Adam, Shao, Wei, Wiegand, Ann, Simonetti, Francesco R., Mellors, John W., Hughes, Stephen H., Coffin, John M., Maldarelli, Frank, Kearney, Mary F.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6781911/
https://ncbi.nlm.nih.gov/pubmed/31632364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.02204
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