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HIV-1 Infection Leads to Increased Transcription of Human Endogenous Retrovirus HERV-K (HML-2) Proviruses In Vivo but Not to Increased Virion Production

Recent studies suggest that human endogenous retrovirus group K (HERV-K) provirus expression plays a role in the pathogenesis of HIV-1 infection. In particular, RNA from the HML-2 subgroup of HERV-K proviruses has been reported to be highly expressed at the cellular level and detectable in the plasm...

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Autori principali: Bhardwaj, Neeru, Maldarelli, Frank, Mellors, John, Coffin, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178833/
https://ncbi.nlm.nih.gov/pubmed/25056891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01623-14
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