Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes

Many tested vaccines fail to provide protection against disease despite the induction of antibodies that bind the pathogen of interest. In light of this, there is much interest in rationally designed subunit vaccines that direct the antibody response to protective epitopes. Here, we produced a panel...

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Foilsithe in:J Exp Med
Main Authors: Bancroft, Tara, DeBuysscher, Blair L., Weidle, Connor, Schwartz, Allison, Wall, Abigail, Gray, Matthew D., Feng, Junli, Steach, Holly R., Fitzpatrick, Kristin S., Gewe, Mesfin M., Skog, Patrick D., Doyle-Cooper, Colleen, Ota, Takayuki, Strong, Roland K., Nemazee, David, Pancera, Marie, Stamatatos, Leonidas, McGuire, Andrew T., Taylor, Justin J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Rockefeller University Press 2019
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780997/
https://ncbi.nlm.nih.gov/pubmed/31345930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190164
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