Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes

Many tested vaccines fail to provide protection against disease despite the induction of antibodies that bind the pathogen of interest. In light of this, there is much interest in rationally designed subunit vaccines that direct the antibody response to protective epitopes. Here, we produced a panel...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Bancroft, Tara, DeBuysscher, Blair L., Weidle, Connor, Schwartz, Allison, Wall, Abigail, Gray, Matthew D., Feng, Junli, Steach, Holly R., Fitzpatrick, Kristin S., Gewe, Mesfin M., Skog, Patrick D., Doyle-Cooper, Colleen, Ota, Takayuki, Strong, Roland K., Nemazee, David, Pancera, Marie, Stamatatos, Leonidas, McGuire, Andrew T., Taylor, Justin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780997/
https://ncbi.nlm.nih.gov/pubmed/31345930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190164
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