Detection and activation of HIV broadly neutralizing antibody precursor B cells using anti-idiotypes

Many tested vaccines fail to provide protection against disease despite the induction of antibodies that bind the pathogen of interest. In light of this, there is much interest in rationally designed subunit vaccines that direct the antibody response to protective epitopes. Here, we produced a panel...

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Bibliographic Details
Published in:J Exp Med
Main Authors: Bancroft, Tara, DeBuysscher, Blair L., Weidle, Connor, Schwartz, Allison, Wall, Abigail, Gray, Matthew D., Feng, Junli, Steach, Holly R., Fitzpatrick, Kristin S., Gewe, Mesfin M., Skog, Patrick D., Doyle-Cooper, Colleen, Ota, Takayuki, Strong, Roland K., Nemazee, David, Pancera, Marie, Stamatatos, Leonidas, McGuire, Andrew T., Taylor, Justin J.
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2019
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780997/
https://ncbi.nlm.nih.gov/pubmed/31345930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190164
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