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Diverse Recombinant HIV-1 Envs Fail To Activate B Cells Expressing the Germline B Cell Receptors of the Broadly Neutralizing Anti-HIV-1 Antibodies PG9 and 447-52D

Broadly neutralizing antibodies (bNAbs) against HIV-1 are generated during HIV-1-infection but have not yet been elicited by immunization with recombinant forms of the viral envelope glycoprotein (Env; the target of anti-HIV-1 neutralizing antibodies). A particular type of bNAb targets the CD4-bindi...

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Autori principali: McGuire, Andrew T., Glenn, Jolene A., Lippy, Adriana, Stamatatos, Leonidas
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958080/
https://ncbi.nlm.nih.gov/pubmed/24352455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03228-13
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