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Antigen modification regulates competition of broad and narrow neutralizing HIV antibodies

Some HIV-infected individuals develop broadly neutralizing antibodies (bNAbs), whereas most develop antibodies that neutralize only a narrow range of viruses (nNAbs). bNAbs, but not nNAbs, protect animals from experimental infection and are likely a key component of an effective vaccine. nNAbs and b...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: McGuire, Andrew T., Dreyer, Anita M., Carbonetti, Sara, Lippy, Adriana, Glenn, Jolene, Scheid, Johannes F., Mouquet, Hugo, Stamatatos, Leonidas
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290850/
https://ncbi.nlm.nih.gov/pubmed/25504724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1259206
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