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Broadly Neutralizing Antibodies Developed by an HIV-Positive Elite Neutralizer Exact a Replication Fitness Cost on the Contemporaneous Virus

Approximately 1% of those infected with HIV-1 develop broad and potent serum cross-neutralizing antibody activities. It is unknown whether or not the development of such immune responses affects the replication of the contemporaneous autologous virus. Here, we defined a pathway of autologous viral e...

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Detalhes bibliográficos
Main Authors: Sather, D. Noah, Carbonetti, Sara, Kehayia, Jenny, Kraft, Zane, Mikell, Iliyana, Scheid, Johannes F., Klein, Florian, Stamatatos, Leonidas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497623/
https://ncbi.nlm.nih.gov/pubmed/22973035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01893-12
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