Soluble HIV-1 Envelope Immunogens Derived from an Elite Neutralizer Elicit Cross-Reactive V1V2 Antibodies and Low Potency Neutralizing Antibodies

We evaluated four gp140 Envelope protein vaccine immunogens that were derived from an elite neutralizer, subject VC10042, whose plasma was able to potently neutralize a wide array of genetically distinct HIV-1 isolates. We sought to determine whether soluble Envelope proteins derived from the viruse...

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Hlavní autoři: Carbonetti, Sara, Oliver, Brian G., Glenn, Jolene, Stamatatos, Leonidas, Sather, D. Noah
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3900663/
https://ncbi.nlm.nih.gov/pubmed/24466285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086905
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