Development of a VRC01-class germline targeting immunogen derived from anti-idiotypic antibodies

An effective HIV-1 vaccine will likely need to elicit broadly neutralizing antibodies (bNAbs). Broad and potent VRC01-class bNAbs have been isolated from multiple infected individuals, suggesting that they could be reproducibly elicited by vaccination. Several HIV-1 envelope-derived germline-targeti...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Seydoux, Emilie, Wan, Yu-Hsin, Feng, Junli, Wall, Abigail, Aljedani, Safia, Homad, Leah J., MacCamy, Anna J., Weidle, Connor, Gray, Matthew D., Brumage, Lauren, Taylor, Justin J., Pancera, Marie, Stamatatos, Leonidas, McGuire, Andrew T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8127986/
https://ncbi.nlm.nih.gov/pubmed/33951425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2021.109084
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