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Germline Targeting Immunogens

In 2009 D. Dimitrov’s group reported that the inferred germline (iGL) forms of several HIV-1 broadly neutralizing antibodies (bNAbs), did not display measurable binding to a recombinant gp140 Env protein (derived from the dual-tropic 89.6 virus), which was efficiently recognized by the mature (somat...

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Bibliographic Details
Published in:Immunol Rev
Main Authors: Stamatatos, Leonidas, Pancera, Marie, McGuire, Andrew T.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741082/
https://ncbi.nlm.nih.gov/pubmed/28133796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12483
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