Structural basis for germline antibody recognition of HIV-1 immunogens

Efforts to elicit broadly neutralizing antibodies (bNAbs) against HIV-1 require understanding germline bNAb recognition of HIV-1 envelope glycoprotein (Env). The VRC01-class bNAb family derived from the VH1-2*02 germline allele arose in multiple HIV-1–infected donors, yet targets the CD4-binding sit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:eLife
Main Authors: Scharf, Louise, West, Anthony P, Sievers, Stuart A, Chen, Courtney, Jiang, Siduo, Gao, Han, Gray, Matthew D, McGuire, Andrew T, Scheid, Johannes F, Nussenzweig, Michel C, Stamatatos, Leonidas, Bjorkman, Pamela J
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Biophysics and Structural Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811768/
https://ncbi.nlm.nih.gov/pubmed/26997349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13783
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados