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Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody
Efforts to design an effective antibody-based vaccine against HIV-1 would benefit from understanding how germ-line B-cell receptors (BCRs) recognize the HIV-1 gp120/gp41 envelope spike. Potent VRC01-like (PVL) HIV-1 antibodies derived from the VH1-2*02 germ-line allele target the conserved CD4 bindi...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3625305/ https://ncbi.nlm.nih.gov/pubmed/23524883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303682110 |
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