Anti-idiotypic antibodies elicit anti-HIV-1–specific B cell responses

Human anti-HIV-1 broadly neutralizing antibodies (bNAbs) protect against infection in animal models. However, bNAbs have not been elicited by vaccination in diverse wild-type animals or humans, in part because B cells expressing the precursors of these antibodies do not recognize most HIV-1 envelope...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Dosenovic, Pia, Pettersson, Anna-Klara, Wall, Abigail, Thientosapol, Eddy S., Feng, Junli, Weidle, Connor, Bhullar, Komal, Kara, Ervin E., Hartweger, Harald, Pai, Joy A., Gray, Matthew D., Parks, K. Rachael, Taylor, Justin J., Pancera, Marie, Stamatatos, Leonidas, Nussenzweig, Michel C., McGuire, Andrew T.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780999/
https://ncbi.nlm.nih.gov/pubmed/31345931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190446
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