HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells

A small number of HIV-1–infected individuals develop broadly neutralizing antibodies to the virus (bNAbs). These antibodies are protective against infection in animal models. However, they only emerge 1–3 yr after infection, and show a number of highly unusual features including exceedingly high lev...

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Bibliografski detalji
Izdano u:J Exp Med
Glavni autori: Hartweger, Harald, McGuire, Andrew T., Horning, Marcel, Taylor, Justin J., Dosenovic, Pia, Yost, Daniel, Gazumyan, Anna, Seaman, Michael S., Stamatatos, Leonidas, Jankovic, Mila, Nussenzweig, Michel C.
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2019
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547862/
https://ncbi.nlm.nih.gov/pubmed/30975893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190287
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