HIV-specific humoral immune responses by CRISPR/Cas9-edited B cells

A small number of HIV-1–infected individuals develop broadly neutralizing antibodies to the virus (bNAbs). These antibodies are protective against infection in animal models. However, they only emerge 1–3 yr after infection, and show a number of highly unusual features including exceedingly high lev...

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Vydáno v:J Exp Med
Hlavní autoři: Hartweger, Harald, McGuire, Andrew T., Horning, Marcel, Taylor, Justin J., Dosenovic, Pia, Yost, Daniel, Gazumyan, Anna, Seaman, Michael S., Stamatatos, Leonidas, Jankovic, Mila, Nussenzweig, Michel C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6547862/
https://ncbi.nlm.nih.gov/pubmed/30975893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20190287
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