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RNA Editing with CRISPR-Cas13
Nucleic acid editing holds promise for treating genetic disease, particularly at the RNA level, where disease-relevant sequences can be rescued to yield functional protein products. Type VI CRISPR-Cas systems contain the programmable single-effector RNA-guided RNases Cas13. Here, we profile Type VI...
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| Udgivet i: | Science |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5793859/ https://ncbi.nlm.nih.gov/pubmed/29070703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaq0180 |
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