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RNA Editing with CRISPR-Cas13

Nucleic acid editing holds promise for treating genetic disease, particularly at the RNA level, where disease-relevant sequences can be rescued to yield functional protein products. Type VI CRISPR-Cas systems contain the programmable single-effector RNA-guided RNases Cas13. Here, we profile Type VI...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Science
Egile Nagusiak: Cox, David B.T., Gootenberg, Jonathan S., Abudayyeh, Omar O., Franklin, Brian, Kellner, Max J., Joung, Julia, Zhang, Feng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793859/
https://ncbi.nlm.nih.gov/pubmed/29070703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaq0180
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