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Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
Rapid detection of nucleic acids is integral for clinical diagnostics and biotechnological applications. We recently developed a platform termed SHERLOCK (Specific High Sensitivity Enzymatic Reporter UnLOCKing) that combines isothermal pre-amplification with Cas13 to detect single molecules of RNA o...
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| Publicado no: | Science |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5961727/ https://ncbi.nlm.nih.gov/pubmed/29449508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaq0179 |
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