RNA targeting with CRISPR-Cas13a

RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. For example, RNA interference (RNAi)(1-3) can efficiently knockdown RNAs, but it is prone to off-target effects(4), and visualizing RNAs typically relies on the introduction of exogenous...

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Bibliografische gegevens
Gepubliceerd in:Nature
Hoofdauteurs: Abudayyeh, Omar O., Gootenberg, Jonathan S., Essletzbichler, Patrick, Han, Shuo, Joung, Julia, Belanto, Joseph J., Verdine, Vanessa, Cox, David B.T., Kellner, Max J., Regev, Aviv, Lander, Eric S., Voytas, Daniel F., Ting, Alice Y., Zhang, Feng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706658/
https://ncbi.nlm.nih.gov/pubmed/28976959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24049
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