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RNA targeting with CRISPR-Cas13a
RNA plays important and diverse roles in biology, but molecular tools to manipulate and measure RNA are limited. For example, RNA interference (RNAi)(1-3) can efficiently knockdown RNAs, but it is prone to off-target effects(4), and visualizing RNAs typically relies on the introduction of exogenous...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5706658/ https://ncbi.nlm.nih.gov/pubmed/28976959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature24049 |
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