Cpf1 is a single RNA-guided endonuclease of a Class 2 CRISPR-Cas system

The microbial adaptive immune system CRISPR mediates defense against foreign genetic elements through two classes of RNA-guided nuclease effectors. Class 1 effectors utilize multi-protein complexes, whereas Class 2 effectors rely on single-component effector proteins such as the well-characterized C...

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發表在:Cell
Main Authors: Zetsche, Bernd, Gootenberg, Jonathan S., Abudayyeh, Omar O., Slaymaker, Ian M., Makarova, Kira S., Essletzbichler, Patrick, Volz, Sara, Joung, Julia, van der Oost, John, Regev, Aviv, Koonin, Eugene V., Zhang, Feng
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4638220/
https://ncbi.nlm.nih.gov/pubmed/26422227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.09.038
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