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Origins and evolution of CRISPR-Cas systems
CRISPR-Cas, the bacterial and archaeal adaptive immunity systems, encompass a complex machinery that integrates fragments of foreign nucleic acids, mostly from mobile genetic elements (MGE), into CRISPR arrays embedded in microbial genomes. Transcripts of the inserted segments (spacers) are employed...
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| Udgivet i: | Philos Trans R Soc Lond B Biol Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6452270/ https://ncbi.nlm.nih.gov/pubmed/30905284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2018.0087 |
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