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Structural basis for potent neutralization of SARS-CoV-2 and role of antibody affinity maturation
SARS-CoV-2 is a betacoronavirus virus responsible for the COVID-19 pandemic. Here, we determined the X-ray crystal structure of a potent neutralizing monoclonal antibody, CV30, isolated from a patient infected with SARS-CoV-2, in complex with the receptor binding domain (RBD). The structure reveals...
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| Publicat a: | bioRxiv |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7301900/ https://ncbi.nlm.nih.gov/pubmed/32577631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.06.12.148692 |
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